Cellular Trajectory Workshop 2024

5-6th September, Imperial College London

We are organising a 2-day workshop that brings together experts combining single-cell analyses with modelling and inference to understand cellular trajectories.

Each participant will be given approximately 40 minutes for a chalk talk with 1-2 supporting data slides, to foster active discussions and blue-sky thinking. This will be an open discussion with integrated Q&A. The workshop and meals, including BBQ and conference dinner, are free for all speakers and are supported by a UKRI Future Leader Fellowship (to PT).

There are a limited number of places available to attend the workshop. If you would like to attend, please email j.pausch15@imperial.ac.uk to register. Lunch and refreshments will be provided.

The venue is 58 Prince's Gate, Imperial College London, UK. See map.

Organisers: Alexis Barr, Johannes Pausch, Paul Piho, Philipp Thomas.

Workshop schedule

Thursday 5th September

Time Speaker Title
9:00 Coffee and pastries
9:30 Alexander Loewer (TU Darmstadt) Integration of stimulus- and state-specific information in SMAD-mediated cellular decisions
10:15 Arthur Radley (Crick) Feature selection: An underappreciated step in single cell data analysis
11:00 Coffee break
11:20 Maria Secrier (UCL) Capturing cell state switches and local adaptation in cancer through AI and ecology-inspired approaches
12:05 Ruben Perez-Carrasco (Imperial) Deciphering tempo control in embryo development through dynamical system theory
12:50 Lunch
13:50 Fabian Frohlich (Crick) Cellular trajectories through the lens of signaling and plasiticity.
14:35 Helen Matthews (Sheffield) Understanding the cellular response to KRAS-targeted cancer therapies
15:20 Coffee Break
15:40 Bartlomiej Waclaw (IChF PAN) Antimicrobial resistance – from cells to populations
16:25 Abhyudai Singh (Delaware) Cell-state transitions and biological timekeeping with stochastic gene expression
18:00 BBQ

Friday 6th September

Time Speaker Title
9:00 Coffee and pastries
9:30 Edo Kussell (NYU) Evolutionary advantage of cell size control
10:15 Bruno Martins (Warwick) Amplitude modulation and frequency modulation in the cyanobacterial clock
11:00 Coffee break
11:20 Andrea Weisse (Edinburgh) The role of RNA repair in transient resistance to translation-targeting antibiotics
12:05 Jakob Ruess (INRIA Paris) Using single-cell models to understand and control emerging population dynamics of an artificial differentiation system in yeast
12:50 Lunch
13:50 Chiara Enrico Bena (INRAE) Real-time monitoring of replication errors’ fate in single Escherichia coli cells reveals the origin and dynamics of spontaneous mutations
14:35 James Locke (Cambridge) Understanding how cellular noise leads to plant-level variability
15:20 Coffee Break
15:40 Jamie Dean (UCL) Functional consequences of a p53-MDM2-p21 incoherent feedforward loop
16:25 Vahid Shahrezaei (Imperial) Inferring mechanisms of stochastic gene expression from single cell snap shot transcription data
19:00 Workshop dinner (for speakers) Ognisko Restaurant, 55 Exhibition Road, SW7 2PG